Proteases are essential ingredients in the detergent formulation because of the uniqueness of their properties. The keratinolytic proteases will add more to the value of proteases in detergent formulation due to their ability to degrade the recalcitrant and insoluble keratin and their ruggedness like stability at high temperature and pH, activity at wide range of temperature and pH, high tolerance for surfactants, oxidizing and bleaching agents, chelating agents, and compatibility with some commercial laundrydetergent